Remote intramolecular functionalization of arylnitrenium ions. ipso-substitution and spiro-lactone formation
نویسندگان
چکیده
منابع مشابه
An effective synthesis of 5,4'-disubstituted flavones via a cesium enolate assisted intramolecular ipso-substitution reaction.
A variety of 5,4'-disubstituted flavones, which are anticipated to be androgen receptor antagonists to treat diseases mediated by the androgen receptor, were synthesized. It was found that an intramolecular ipso-substitution reaction via cesium enolate using 2-fluoro-6-hydroxyacetophenone and various benzoyl chlorides was effective in the preparation of 5-hydroxy-4'-alkylflavones.
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ژورنال
عنوان ژورنال: Journal of the Chemical Society, Chemical Communications
سال: 1986
ISSN: 0022-4936
DOI: 10.1039/c39860000283